Purdue vs. Iowa State prediction, odds, spread: 2025 college basketball picks from proven model

Undefeated teams meet in an early tipoff on Saturday when the top-ranked Purdue Boilermakers host the No. 10 Iowa State Cyclones. Iowa State is off to a strong start with wins over Mississippi State, Creighton, St. John’s and Syracuse already on its resume. Purdue, meanwhile, has defeated Alabama, Rutgers, Memphis and Texas Tech so far. Both teams have also played their last three matches, setting up a heavyweight top-10 battle.

Tipoff from Mackey Arena is set for noon ET. The Boilermakers are 6.5-point favorites in the latest Purdue vs. odds. Iowa State, while the over/under is 153.5. Before you make your choice between Iowa State and Purdue, check out the men’s basketball predictions and betting advice from the SportsLine projection model.

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The SportsLine projection model simulates every college basketball game 10,000 times and has produced more than $2,000 in betting winnings for $100 players on the top-rated college basketball picks over the past three seasons. Anyone who follows college basketball betting advice sports books and on gambling apps could have yielded huge returns.

Now the model has been simulated Purdue vs. Iowa State 10,000 times and just unveiled the coveted men’s basketball picks and betting predictions. That’s possible head over to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting odds for Iowa State vs. Purdue:

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How to watch Purdue vs. Iowa State choices

The SportsLine model is Going to the total (160 points). Six of Iowa State’s eight games this season have gone over the total, including three of the four on the road. Meanwhile, Purdue has lost three of its four home games.

The model predicts eight players will reach double figures in this match, with Iowa State’s Joshua Jefferson and Purdue’s Trey Kaufman-Renn leading their respective teams in scoring. The model predicts the teams will combine for 160 points, with the Over hitting almost 70% of the time.

The SportsLine model says one side of the spread hits in more than 60% of simulations. You will only see that choice at SportsLine.

So who wins Iowa State vs. Purdue, and which side of the spread hits more than 60% of the time? Visit SportsLine now to see which side of the spread everything from the advanced model was profitable on the top college basketball picks last seasonand find out.