With Week 15 of the NFL season upon us, we used our advanced predictive analytics model to create a list of NFL instant picks for all 16 games this week.
Secure an advantage in your NFL pick ’em competitions through our data-driven NFL Week 15 continues immediatelypowered by thousands of game simulations.
Week 15 of the NFL season features 16 games, starting with the Atlanta Falcons versus the Tampa Bay Buccaneers on Thursday night and ending with the Miami Dolphins versus the Pittsburgh Steelers on Monday night.
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The full NFL Week 15 list will pop up right away
- Buccaneers (68% chance of winning)
- Giants (58%)
- Eagles (88%)
- Bears (78%)
- Raven (56%)
- Texans (79%)
- Bills (56%)
- Jaguars (87%)
- Leaders (67%)
- Seahawks (89%)
- 49ers (86%)
- Packers (57%)
- Panthers (60%)
- Rams (67%)
- Cowboys (73%)
- Steelers (60%)
NFL picks immediately this week: Week 15, 2025
Below are our Week 15 NFL picks, which highlight how likely each team is to win its game this week.
Atlanta Falcons vs. Tampa Bay Buccaneers
The Falcons kick off Week 15 against the Buccaneers on Thursday evening at Raymond James Stadium. According to our NFL model, the Buccaneers have a 68% chance of winningwhile the Falcons have a 32% chance.
For the opening game of Week 15, our model highlights NFL players’ props with Sesame Robinson (RB) as the Falcons’ most likely player to score the first TD at 11.6%, while Mike Evans (WR) is the Buccaneers’ top prospect at 10.5%.
The Atlanta Falcons vs. Tampa Bay Buccaneers The match at Raymond James Stadium is scheduled for Thursday, December 11 at 8:15 PM. All times in this article are in Eastern Standard Time (EST).
Washington Commanders vs. New York Giants
For this week’s game between the Commanders and the Giants, there is a better chance that the NY Giants will win. Our prediction model gives the Giants have a 58% chance of winning. On the other hand, there is a 42% chance that the Commanders will win.
The Washington Commanders vs. New York Giants The match at MetLife Stadium will take place on Sunday, December 14 at 1:00 PM.
As the playoffs approach, keep up with the top teams with Dimers’ updated NFL Futures, highlighting the top Super Bowl contenders.
Las Vegas Raiders vs. Philadelphia Eagles
We pick the Eagles to win their game against the Raiders this week, with our famous NFL model projecting an 88% win probability for the home team. The Raiders have a 12% chance of winning.
For betting purposes, the Eagles are listed as -11.5 favorites, with the Raiders’ moneyline at +625.
The Las Vegas Raiders vs. Philadelphia Eagles The game at Lincoln Financial Field is scheduled for Sunday, December 14 at 1 p.m.
Cleveland Browns vs. Chicago Bears
According to our predictive analytics model, the Bears are the team to beat in this game, with a 78% chance of winning. The Browns, on the other hand, have a 22% chance of winning.
The Cleveland Browns vs. Chicago Bears at Soldier Field is scheduled for Sunday, December 14 at 1 p.m.
Baltimore Ravens vs. Cincinnati Bengals
The Ravens have a 56% chance of winning on Sunday afternoon, compared to the Bengals’ 44% chance of winning. This makes the Baltimore Ravens our pick to win at Paycor Stadium.
The Baltimore Ravens vs. Cincinnati Bengals game at Paycor Stadium is scheduled for Sunday, Dec. 14 at 1 p.m.
Arizona Cardinals vs. Houston Texans
The Texans are favorites to win this game, with our predictive analytics model giving them a 79% chance, while the Cardinals enter the weekend with a 21% chance of causing an upset at NRG Stadium.
When it comes to betting on this game, the Cardinals’ moneyline odds are set at +440, with the home Texans as -9.5 favorites.
The Arizona Cardinals vs. Houston Texans at NRG Stadium takes place on Sunday, December 14 at 1:00 PM.
Buffalo Bills vs. New England Patriots
After 10,000 simulations of Bills vs. Patriots this Sunday, our model projects the Bills as the most likely winners with a probability of 56%. Their opponents, the Patriots, have a 44% chance of winning at home.
The Buffalo Bills vs. New England Patriots game at Gillette Stadium is scheduled for Sunday, December 14 at 1 p.m.
New York Jets vs. Jacksonville Jaguars
Our model chooses the Jaguarswho have an 87% chance of winning the game, while the Jets have a 13% chance of winning.
The New York Jets vs. Jacksonville Jaguars game at EverBank Stadium will take place on Sunday, December 14 at 1:00 PM.
Los Angeles Chargers vs. Kansas City Chiefs
In the next Week 15 game, the Chargers will take on the Chiefs at GEHA Field at Arrowhead Stadium.
We predict the Chiefs will win with a 67% probability, while the Chargers are projected to have a 33% chance of winning.
As for the Vegas betting odds here, the Chiefs are listed as -4.5 favorites, while the Chargers’ moneyline odds are listed at +180.
The Los Angeles Chargers vs. Kansas City Chiefs at GEHA Field at Arrowhead Stadium is scheduled for Sunday, December 14 at 1 p.m.
Indianapolis Colts vs. Seattle Seahawks
The likely winner of this matchup is the Seahawkswhich according to DimersBOT have an expected win probability of 89%. On the other side of this matchup, the Colts have an expected win probability of 11%.
The Indianapolis Colts-Seattle Seahawks game at Lumen Field is scheduled for Sunday, December 14 at 4:25 PM.
Tennessee Titans vs. San Francisco 49ers
We ran our powerful NFL model on this week’s Titans-49ers clash 10,000 times, with the 49ers emerge as the team to pick. Of those 10,000 simulations, the 49ers won 8,649 times, while the Titans won 1,351 times.
The Tennessee Titans vs. San Francisco 49ers at Levi’s Stadium is scheduled for Sunday, December 14 at 4:25 PM.
Green Bay Packers vs. Denver Broncos
Next up is the game between the Packers and the Broncos, with our model projecting the road team as the most likely winner, with the Packers estimate they have a 57% chance of winning the W. The Broncos, on the other hand, are projected to have a 43% chance of winning.
For those interested in betting on this matchup, the oddsmakers have set the Packers’ moneyline odds at -135 for this road game, while the hosting Broncos are listed as +2.5 underdogs.
The Green Bay Packers vs. Denver Broncos at Empower Field at Mile High will take place on Sunday, December 14 at 4:25 p.m.
Carolina Panthers vs. New Orleans Saints
Our next pick this week is for the Panthers to get the win against the saints. After running 10,000 simulations of this matchup, the Carolinas have a 60% win probability, while the Saints have 40%.
The Carolina Panthers vs. New Orleans Saints at Caesars Superdome is scheduled for Sunday, December 14 at 4:25 PM.
Detroit Lions vs. Los Angeles Rams
With a 67% chance of winning on Sunday afternoon, our immediate choice for this matchup is the Ramswhile their opponent, the Lions, has a projected win probability of 33%.
The Detroit Lions vs. Los Angeles Rams at SoFi Stadium takes place on Sunday, December 14 at 4:25 PM.
For a different take on this week’s NFL action, explore our NFL Trends to find the latest trends in player accessories.
Minnesota Vikings vs. Dallas Cowboys
The The team to pick here is the Cowboyswho have a 73% chance of winning their game against the Vikings this Sunday night.
Looking at the betting odds for this Sunday Night Football clash, the Cowboys are listed as -6 favorites at home, while the Vikings’ moneyline odds are available at +240.
The Minnesota Vikings vs. Dallas Cowboys game at AT&T Stadium is scheduled for Sunday, December 14 at 8:20 PM.
Miami Dolphins vs. Pittsburgh Steelers
Us The pick to win the final game of Week 15 is the Steelerswhich have a 60% chance of winning. Their opponents are expected to have a 40% chance of winning the W.
The Miami Dolphins vs. Pittsburgh Steelers at Acrisure Stadium is scheduled for Monday, December 15 at 8:15 p.m.
For more insight into this week’s NFL predictions, check out the latest from the Dimers Sports Betting Podcast:
NFL instant picks and predictions for week 15
The NFL Week 15 predictions straight up in this article are correct at the time of publication, but may change.
Dimers.com is the best site for NFL predictions, with our clear picks trusted by football fans across the country.
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Please note that all NFL odds and odds listed on this page are subject to change.
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