Every surface of our body, from the lungs to the bladder, has a unique composition of microorganisms. The enormous microbial diversity is mainly found in the digestive tract, which is crucial for good intestinal health, but also disorders that may not seem to be with your intestines, including cardiovascular health, skin problems and neurological diseases, among other things. Although what we know so far about the relationship between intestinal microbiota and other organs comes from studying intestinal bacteria, but others such as fungi, yeast, viruses and parasites also come to the party.
One of the most studied areas is the relationship between the intestine and the brain. Microbes in your intestines are constant Talk to your braincontribute to stress and our emotions, but the opposite is also possible. In addition to microbes, the intestinal brain connection includes the vagus nerve, hormones, immune cells and metabolites, all of whom work as a team to leave the two-way street between the intestine and the brain.
The implications of these findings suggest that the microbiome can play a role in the development of dementia, autism and other disorders. However, we still do not know whether a changed microbiome is the cause of brain disorders or only a effect.
Intestinal microbes can also be a hidden cause of lung diseases that are difficult to control. It appears that the intestinal microbiota is connected to the lung microbiota, where the latter is mainly formed by the Oropharynx -microbioma, which varies between individuals but remains stable over time. Scientists investigate how they can use commensal microbes in the lung to predict asthmatic torches and improve the response to current drugs for lung diseases. Some studies have also suggested that a vegetable diet is essential to keep inflammation at bay and to offer the necessary nutrients to support the immune system and intestinal microbioma that are relevant to the health of the airways.
The intestine is an access door to our body and intestinal microbiota helps to create the immune system a barrier against pathogens. Up to 80% of the immune cells are in the intestine. Looking for a remedy for irritable bowel syndrome, researchers have themselves The increased activation of immune refill in the small intestine. These findings support that gastrointestinal problems are not in the heads of patients.
The high fermentation of carbohydrates in the colon is not the only culprit of symptoms, because scientists theoretize that a belly infection can temporarily change the intestinal barrier. With the disturbed barrier, some food components can be absorbed and localized allergic reactions. However, it is too early to recommend IgG -based elimination songs for patients with IBS who use exclusion diets for symptom management.
Close to the intestine, the liver plays a crucial role in the metabolism of food. For healthy people, the liver works as a gatekeeper and removes the removal of toxic connections before they enter the bloodstream. When the intestinal barrier is disturbed, micro -organisms and their metabolites can enter the liver. Scientists are investigating new ways to modulate the intestine and liver to reduce the complications of liver diseases.
The skin is one of the most extensive surfaces of the body and is also connected to what happens in our gut. But unlike intestinal microbioma, the skin microbioma is more independent. The relationship between the intestine and the skin was initially introduced in 2016. Recent studies have shown that an unbalanced intestinal microbiome can weaken the intestinal wall, a condition that is already linked to eczema, psoriasis, vitiligo and acne.
Last but not least, the study of heart health through the lens of gut microbes can help understand why not everyone’s metabolism responds to diet in the same way. Scientists and doctors start to recognize increased blood levels of trimethylamine N-oxide (TMAO)- a connection derived from diet (eg choline, carnitine) and the microbiome as a marker that can be used to identify patients with a higher risk of heart disease. Scientists are looking for new targeted treatments that inhibits the conversion of nutritional connections into TMAO by modulating the intestinal microbioma and using individual intestinal microbrobi -compromes to personalize nutritional advice.
Read more in this video about how the intestinal microbiome is connected to organs outside the gut and why this is important for improving health:
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