Pistons vs. Celtics NBA odds, preview, picks and predictions

Pistons vs. Celtics NBA odds, preview, picks and predictions

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A nine-game NBA series on Wednesday will be headlined by an ESPN triple-header that begins with the Detroit Pistons visiting the Boston Celtics at 5:00 PM ET. Detroit has risen to a 15-2 record, while Boston is struggling a bit at 9-8.

Let’s dive into my Pistons vs. Celtics predictions dive.

Detroit Pistons vs. Boston Celtics Odds

Moneyline: Pistons -162 / Celtics +136
Spread: Pistons -3 (-110) / Celtics +3 (-110)
Total: More than 228.5 (-110) / Less than 228.5 (-110)

Detroit Pistons vs. Boston Celtics Best Bet No. 1: Pistons -3 (-110)

Seventeen games into the 2025-2026 campaign, the sample size is large enough to confirm that Detroit is the real deal. Since the start of the season at 2-2, the team has won thirteen games in a row, six of which in a row with a difference of at least five points. Former No. 1 pick Cade Cunningham is in MVP form, averaging 27.1 points, 9.6 assists, 6.0 rebounds and 1.3 steals per game. Cunningham also gets a lot of help, as seven other teammates score in double figures. That includes big man Jalen Duren (20.3 ppg, 11.5 rpg), who has delivered six double-doubles in the last eight games — a stretch that included a 22-point, 22-rebound effort against the Jazz.

For Jaylen Brown, it’s a very different story in Boston. Jayson Tatum is out with a torn Achilles tendon and both Kristaps Porzingis and Al Horford left last season. Brown isn’t a complete one-man show as Derrick White, Payton Pritchard, and Anfernee Simons make solid contributions, but Brown’s supporting cast is nothing like Cunningham’s. The Celtics’ normal starting lineup consists of Jordan Walsh and – when healthy – Neemias Queta. You may be wondering, “who?!?!” As for Brown, he is an abysmal 14-for-57 (24.6 percent) from three-point land in 11 games during the month of November.

Detroit Pistons vs. Boston Celtics Best Player Prop Bet: Payton Pritchard Under 4.5 Assists (-125)

Across the board, the offensive numbers could decline in this matchup. Boston plays at the slowest pace in the entire NBA, and faces a stout Detroit defense. The Pistons allow the fewest assists per game in the league (23.2) and the fifth fewest assists per field goal made. They also give up the fourth fewest points in the paint per game.

Where is Pritchard going to throw the ball? The Celtics won’t be able to score down low (especially with Queta being ruled out) and Brown hasn’t been able to throw it into the ocean from the perimeter this month. Pritchard has stayed under that number in six of 11 games in November, recording a modest four assists in a 119-113 loss at Detroit on October 26.

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