North Carolina vs. Kentucky Prediction, Odds, Line: 2025 College Basketball Picks from Proven Model

Ranked teams collide when the No. 17 North Carolina Tar Heels take on the No. 18 Kentucky Wildcats on Tuesday night in one of the premier 2025 ACC/SEC Challenge games. UNC is coming off a 74-58 loss to Michigan State on Thanksgiving Day, while Kentucky defeated Tennessee Tech 104-54 on Wednesday. The Tar Heels (6-1), who finished in fourth place with Wake Forest and SMU in the Atlantic Coast Conference at 13-7, were 23-14 overall a year ago. The Wildcats (5-2), who ranked sixth with Ole Miss and Missouri at 10-8, were 24-12 overall in 2024-25.

Tip-off from Rupp Arena in Lexington, Kentucky, is scheduled for 9:30 PM ET. Kentucky leads the all-time series 25-18, including wins in each of the last two meetings. Kentucky is a 6.5-point favorite in the latest North Carolina vs. Kentucky per SportsLine consensus, while the over/under for total points scored is 163.5. Before you make a choice between Kentucky and UNC, check out the men’s basketball predictions and betting advice from the SportsLine projection model.

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The SportsLine projection model simulates every college basketball game 10,000 times and has produced more than $2,000 in betting winnings for $100 players on the top-rated college basketball picks over the past three seasons. Anyone who follows college basketball betting advice sports books and on gambling apps could have yielded huge returns.

Now the model has been simulated UNC vs. Kentucky 10,000 times and just unveiled the coveted men’s basketball picks and betting predictions. That’s possible head over to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting odds for Kentucky vs. UNC:

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How do you make North Carolina vs. Kentucky picks?

The SportsLine model is Going below on the total (163.5 points). Both teams recently went to the Under. Three straight Kentucky games have hit that team, while UNC has had Under three of its last four games.

The model has only one player – UNC’s Caleb Wilson – projected to score more than 14 points. The teams combine for 163 points, as the Under is the value play.

The mode also says that one side of the spread hits in over 60% of simulations. You will only see that choice at SportsLine.

So who wins North Carolina versus Kentucky, and which side of the spread wins in over 60% of simulations? Visit SportsLine now to see which side of the North Carolina vs. Kentucky running back spread, everything from the advanced model was profitable last season on the top-ranked college basketball picksand find out.