Prediction of Duke vs. Texas, odds, best bets: college basketball picks from proven computer model

While Monday marked the start of the 2025-2026 college basketball season, several teams are waiting until Tuesday to tip off, including a pair of power conference programs. No. 6 Duke and Texas will meet at the 2025 Dick Vitale Invitational, a first-year event. Duke went 35-4 last season and won both the ACC regular season and tournament before bowing out in the Final Four. Texas went 19-16 a year ago and lost in the First Four of March Madness before replacing Rodney Terry with Sean Miller as head coach.

Tipoff is at 8:45 PM ET from the Spectrum Center in Charlotte, NC Duke has won all three previous matchups between the programs. The Blue Devils are favorites by 10.5 points in the latest Duke vs. Texas odds from SportsLine consensus, while the over/under for total points scored is 152.5. Before you make a choice between Texas and Duke, view college basketball predictions and betting advice from SportsLine’s projection model.

New users can focus on the DraftKings Promo Codethat offers $300 in bonus bets if your bet wins + 3 months of NBA League Pass:

The SportsLine projection model simulates every college basketball game 10,000 times and has produced more than $2,200 in betting winnings for $100 players on the top-rated college basketball picks over the past three seasons. Anyone who followed the college basketball betting advice on sportsbooks and betting apps could have seen huge returns.

Now the model has been simulated Duke vs. Texas 10,000 times and just unveiled the coveted men’s basketball picks and betting predictions. That’s possible head over to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting odds for Texas vs. Duke:

Why Texas Can Provide Coverage

The Longhorns return a pair of double-digit scorers in Jordan Pope (11 ppg) and Tramon Mark (10.6), while adding a few more. Lassina Traore comes from Long Beach State, where he was a two-time All-Big West Selection selection and twice led the conference in rebounds. The Longhorns also acquired Matas Vokietaitis from FAU, where the Lithuanian was the American Conference Rookie of the Year last season, averaging 10.2 points, 5.4 rebounds and knocking down 67.7% of his field goal attempts.

Perhaps the biggest addition for Texas is bringing on board coach Sean Miller, who previously served at Xavier and Arizona. He is a four-time winner of his conference’s Coach of the Year award and is known for getting the best out of his players, especially on the offensive end of the court. That’s an area where Texas can challenge Duke, as the Blue Devils lost two ACC All-Defensive players to the NBA Draft, including the AP Player of the Year in Cooper Flagg. See which team to support at SportsLine.

Why Duke can cover

Duke simply reloaded after losing Flagg and four others to the pros, as the team has the No. 1 incoming freshman class according to 247Sports. That class is highlighted by Cameron Boozer, who is the third overall recruit and one of four athletes ever to win the Gatorade National Player of the Year award twice in high school. His twin brother, Cayden Boozer, is the No. 4 point guard in his class, while Duke also signed two other five-star players: Nikolas Khamenia and Dame Sarr.

It’s not just newcomers to Duke’s roster, as four rotation players return from last year’s squad that made it to the Final Four. Jon Scheyer’s team played 67.7% of its games a year ago, and the Blue Devils have also played two-thirds of their games since 2023 against non-conference opponents. Additionally, Duke can take solace in the fact that Texas struggled as it ramped up its competitiveness, going 0-5 outright against top-10 ranked teams last season. See which team to support at SportsLine.

New users can check out the latest bet365 bonus code Unpleasant receive $200 in bonus bets after placing a $5 bet:

How to Make Duke vs. Texas choices?

The SportsLine model has Texas vs. Duke simulated 10,000 times and leaned over the total, projecting 153 combined points. The model also says that one side is successful in more than 50% of simulations. You can head over to SportsLine to check out the model’s men’s college basketball picks.

So who wins Duke vs. Texas, and which side of the spread hits in over 50% of simulations? Visit SportsLine now to see which side of the Texas vs. Duke spreads to the back, all from the advanced model that has returned more than $2,200 on its college basketball picksand find out.