Indiana vs. Kentucky Prediction, Odds, Spread, Time: 2025 College Basketball Picks According to Proven Model

The Indiana Hoosiers and Kentucky Wildcats renew their rivalry when they meet in non-conference action on Saturday. Indiana is coming off a 113-72 win over Penn State on Tuesday, while Kentucky defeated North Carolina Central 103-67 that same night. The Hoosiers (8-2), who finished ninth in the Big Ten at 10-10 and were 19-13 overall last year, are 0-1 on the road this season. The Wildcats (6-4), who finished sixth in the SEC at 10-8 and were 24-12 in 2024-25, are 6-1 at home this year.

Tip-off from Rupp Arena in Lexington, Kentucky, is scheduled for 7:30 PM ET. Kentucky leads the all-time series 32-25. Kentucky is a 3.5-point favorite in the latest Indiana vs. odds. Kentucky per SportsLine consensus, while the over/under for total points scored is 157.5. Before you make a choice between Kentucky and Indiana, check out the men’s basketball predictions and betting advice from the SportsLine projection model.

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The SportsLine projection model simulates every college basketball game 10,000 times and has produced more than $2,000 in betting winnings for $100 players on the top-rated college basketball picks over the past three seasons. Anyone who follows college basketball betting advice sports books and on gambling apps could have yielded huge returns.

Now the model has been simulated Indiana vs. Kentucky 10,000 times and just unveiled the coveted men’s basketball picks and betting predictions. That’s possible head over to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting odds for Kentucky vs. Indiana:

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How to watch Indiana vs. makes Kentucky choices

The SportsLine model is Moving on to the total (157.5 points). The overhit in three of Indiana’s last four games, while the overhit in Kentucky’s last game.

The model projects the Hoosiers to have six players register 11.1 points or more, led by Lamar Wilkerson’s projected 16.5 points. The Wildcats are expected to have four players score 10.2 or more points, led by Otega Oweh with 14 points. The model projects a combined total of 161 points as the Over disappears in almost 60% of simulations.

The model also says that one side of the spread hits well over 50% of the time. You will only see that choice at SportsLine.

So who wins Indiana vs. Kentucky, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Indiana vs. Kentucky spread to the back, everything from the advanced model was profitable on the top-ranked college basketball picks last seasonand find out.