The Gunners returned to victory in their 4-1 derby demolition match against Tottenham in the North London derby last week, after dropping points against Brentford and Wolves to allow City to eat away at the deficit.
They face Chelsea fueled by frustration after Liam Rosenior’s side were held to a 2-2 draw by Burnley last time out.
Zian Flemming scored a late equalizer as the Blues lost ground in the race for the Champions League places, giving Manchester United the chance to pull away from them.
Michael Carrick’s Red Devils did just that on Monday by beating Everton 1-0, putting United three points ahead of Chelsea as their unbeaten run continued under Carrick.
Arteta has recently suffered a spate of injuries that have made his job more difficult, with Bukayo Saka, Kai Havertz and Ben White all recent concerns.
That adds to the lengthy absence of Mikel Merino, who is absent following surgery for a stress fracture in his foot.
There is some positive news for Gunners fans as teenage sensation Max Dowman could finally return from his long layoff after suffering an ankle injury that kept him out for two months.
How to watch Arsenal vs Chelsea
TV channel: In Great Britain the match will be broadcast live on Sky Sports. Coverage starts at 3.30pm GMT on Sky Sports Main Event and Sky Sports Football.
Live stream: Sky Sports subscribers can also watch the match live online via the Sky Go app.
Live blog: You can follow all the matchday action via Standard sport live blog, with expert analysis from Matt Verri and Dom Smith on site.
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