Can Semaglutide Alzheimer’s prevent?

How Semaglutide influences the health of the brain

Research is underway with regard to the effect of semaglutide on the brain – and most studies have so far involved in animals – but a growing number of research shows that Semaglutide can benefit cognitive function for people with diabetes and/or obesity by improved memory, learning and overall mental performance.

A systematic judgement Discovered that Semaglutide protected the blood-brain barrier, which is responsible for stopping toxins, pathogens (substances that cause diseases) and other harmful substances to leak in the brain.

“Semaglutide can calm brain inflammation, especially in the immune cells of the brain called microglia, and help protect the blood-brain barrier that works as a guard for the brain,” Tousi said. “It also seems to improve blood flow, reduce oxidative stress – a kind of damage that builds up in the brain – and supports brain cell function. All these factors play a role in Alzheimer’s disease.”

Another study Discovered that Semaglutide reversed the signs of aging in important brain cells that help keep our brain clean, protected and balanced. “Age can cause these cells to work, causing inflammation in the brain and causing confusion. Taking semaglutide helped these cells to behave as they would do in younger brains,” Tousi said.

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Tousi also noted that the study discovered that Semaglutide prevented the formation of a type of astrocytes – a brain cell that becomes toxic under stress – which worsens inflammation and damages brain tissue, a process that is also seen in Alzheimer’s disease.

This is similar to the findings of another studyHe noticed that Semaglutide improved cognitive possibilities in mice by performing different functions, one of which reduced the amount of amyloid plaques in the brain. It is thought that amyloid plaques play a role in Alzheimer’s, and this research suggests that Semaglutide may not only play a role in the prevention of Alzheimer’s, but also the Alzheimer’s Alzheimer’s can improve in people who already have it.

Semaglutide for people who are at risk of Alzheimer’s

Type 2 diabetes and obesity are both known risk factors for Alzheimer’s disease. But given the recent findings in human studies, semaglutide can be useful for anyone who is at risk of Alzheimer’s disease.

“Because Semaglutide seems to help reduce inflammation and protect the brain, there is a growing interest in whether it can also benefit people without diabetes, especially people with early memory problems or a strong family history of dementia,” Tousi said. “This can indicate a future in which a common diabetes medicine plays a major role in the health of the brain and even dementia prevention.”

This is especially important to notice for women and people who are assigned at birth (AFAB), because Alzheimer’s is more common in women than men. About 1 in 5 women are diagnosed with Alzheimer’s disease during their lives compared to 1 in 10 men.

There is currently no cure for Alzheimer’s, so progress in treatment options to manage and prevent the disease from being crucial.

Promising new research on the horizon

There is hope on the horizon about the role of semaglutide in preventing or treating Alzheimer’s disease. The results of the First large -scale human study Showing or Semaglutide Alzheimer’s can delay in people with early stages of diseases – even in people without type 2 diabetes – will be released in September.

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Tousi said that the study includes a substitute in which spinal fluid is analyzed to help discover how the medicine works in the brain. The study could give instructions on the exact mechanism of semaglutide and guides future treatments.

“It is also worth noting that Alzheimer’s women find more than men, and early data indicate that the brain benefits of Semaglutide can be even stronger in women,” Tousi said. “These tests should clarify that.”